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专利名称：Synthetic anti-inflammatory derivatives of
manoalide
发明人：Robert S. Jacobs,D. John Faulkner申请号：US06/621879申请日：19840618公开号：US046160A公开日：19861007
摘要：Synthetic analogs of the marine natural product manoalide include 3,7-Bis(hydroxymethyl)-4-hydroxy-11-methyl-13-(2',6',6'- trimethylcyclohexen yl)-2,6,10-tridecatrienoic acid &ggr;-lactone, manoalide &dgr;- lactone, manoalide &dgr;-lactoneacetate and dehydro- seco-manoalide.< P>
The method of treating mammals including humans in need of a drug having analgesicand/or anti- inflammatory activity comprising the administration of a therapeuticallyeffective amount of a synthetic analog of manoalide.
申请人：UNIVERSITY OF CALIFORNIA
代理机构：Ciotti & Murashige
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